MT1 research: overview and resources
What MT1 research material is, how it is characterized, and where to find every specification, method, lot record and reference MT1 Labs publishes about it.
What is MT1?
Melanotan I (MT1) is a synthetic 13-residue analog of α-melanocyte-stimulating hormone (α-MSH), also written [Nle4, D-Phe7]-α-MSH or NDP-α-MSH. It keeps the full linear α-MSH sequence, acetylated at the N-terminus and amidated at the C-terminus, with two substitutions: norleucine replaces methionine at position 4, removing the oxidation-prone sulfur, and D-phenylalanine replaces L-phenylalanine at position 7, which makes the core of the molecule more resistant to enzymes and increases its affinity for the melanocortin 1 receptor (MC1R).
MT1 Labs supplies Melanotan I as a lyophilized powder in 10 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity against a reference standard and net content, with a fentanyl screen, and the certificate is published here before sale through Klow.bio.
MT1 is a linear peptide and a different compound from Melanotan II (MT2), which is a shorter, cyclic analog. The two have different formulas and molecular weights (1646.85 vs 1024.18 g/mol).
What is MT1 research material?
MT1 research material is Melanotan I supplied for laboratory research (C78H111N21O19, 1646.85 g/mol) in lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.
How is MT1 characterized?
Three questions are answered for every lot, each by a different method:
- Is it the right compound? The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time.
- How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 97.55%.
- How much peptide is in the vial? Net content is measured directly.
Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.
What has not been established
A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.
MT1 at a glance
- Product
- Melanotan I
- Type
- Synthetic linear α-MSH analog (13 residues), 13 residues
- Also known as
- MT1, MT-I, [Nle4, D-Phe7]-α-MSH, NDP-α-MSH
- Receptor design
- Melanocortin 1 receptor (MC1R)
- Molecular formula
- C78H111N21O19
- Molecular weight
- 1646.85 g/mol (average)
- Form
- Lyophilized powder
- Vial sizes
- 10 mg
- Purity, current lots
- 97.55% (HPLC-UV)
- Purity specification
- ≥95%
- Identity
- Confirmed by HPLC retention-time match on every lot
- Testing laboratory
- ILS Laboratories (independent)
- Current lot
- KB-34289, reported Sep 12, 2026
- Operated by
- Klow Labs LLC, Chicago, IL
- Where to order
- klow.bio
MT1 research resources
Every MT1 resource on mt1.bio, organized from chemistry to documentation.
MT1 specifications
Formula, molecular weight, sequence, modifications and release specification.
QualityQuality and supply chain
Sourcing, specifications, batch documentation and release.
TestingAnalytical testing
How every lot is tested, reviewed and released.
TestingHPLC analysis of MT1
Retention time, peaks, area normalization and results by lot.
DocumentationCertificates of analysis
Every lot's full results, plus the complete testing records.
DocumentationHow to read a MT1 COA
What each section means and what a COA does and doesn't establish.
DocumentationVerify a lot
Look up any MT1 lot by the number on the vial.
AnalysisPurity, content and net content
Three different numbers, kept apart.
HandlingStorage and stability
Degradation pathways and lyophilized peptide handling.
ReferenceGlossary
Definitions for every term on a MT1 certificate.
Research materialMelanotan I research material
Sizes, current lots and availability. Purchasing is handled through Klow.bio.
Research references
Published sources
- PubChem: Melanotan I. National Library of Medicine, NIH. pubchem.ncbi.nlm.nih.gov/compound/16164658
- NCBI Gene: MC1R (melanocortin 1 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/4157
- NCBI Gene: POMC (proopiomelanocortin, the α-MSH precursor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/5443
- Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
- U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
- U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov
MT1 Labs analytical documentation
- Lot KB-34289: 10 mg, 97.55% purity, reported Sep 12, 2026
- MT1 testing records (all tests, all lots; CSV available)
Editorial scope
MT1 Labs research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.
It does not cover dosing, administration instructions, protocols, personal use or medical advice.
Latest updates
Buy MT1
10 mg vials. Current lot KB-34289 tested at 97.55% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.